What role do formins play in epithelial junctional stability?

steve2018-02-05T14:55:24+08:30

What role do formins play in epithelial junctional stability?

This study addresses the role of formins at epithelial junctions. A major formin, mDia1, is shown to be recruited to Adherens Junctions (AJs) by E-Cadherin and RhoA. This leads to the organization of actomyosin filaments around the AJs which causes an increase in junctional contractility. […]

What is the role of plastin in C. elegans embryogenesis?

steve2018-02-08T13:15:06+08:30

What is the role of plastin in C elegans embryogenesis?

Plastin, an actin cross-linking protein, has been shown to be instrumental for efficient cytokinesis and polarization in C. elegans zygotes. By increasing connectivity within the cortical actomyosin network, plastin provides strength to the network, to enable a coordinated cortical flow required to segregate proteins during zygote polarization. Similarly, […]