Summary
| Title | Formin |
| Description | Formin.This schematic diagram illustrates the molecular organization of formin. Relevant domains/regions that are believed to be important for actin binding and protein-protein interactions are highlighted (reviewed in [2]. An intramolecular interaction between the diaphanous inhibitory domain (DID)and the diaphanous auto-regulatory domain (DAD), which prevents formin (e.g. mDia1) from nucleating actin filaments, is relieved by Rho binding to the GTPase binding domain (GBD, aka CRIB domain) [3]. However, this regulation may be more complex [4, 5]. DD = dimerization domain, FH = formin homology domain |
| Date | 2012 |
| Referred pages | Actin Filament Elongators |
| License | Creative Commons Attribution-NonCommercial 4.0 International License |
| Permission | Modification, copying and distribution (commercial) of this image is strictly prohibited without written consent. Please contact MBInfo at [email protected] to request permission to use this image. |
How to cite this page?
Formin. In MBInfo Wiki, Retrieved 10/21/2014 from http://mbinfo.mbi.nus.edu.sg/figure/1384240860778/
