The goal of mechanobiology is to understand the functional effects of the structural micro-environment and force-induced deformations. These factors, when combined with chemical signals, determine the local cell response that is integrated to drive multicellular functions in whole organisms.
MBInfo is a unique, multipurpose information resource, created at the Mechanobiology Institute, Singapore. MBInfo provides in-depth reviews on the mechanics of cellular and molecular function. Through its wiki-based design, reviews are updated regularly to keep pace with progress within the field. Each review is written by scientists and subsequently peer reviewed by experts in the field to ensure the content is accurate, reliable and up to date.
This resource deals with the process of mechanotransduction. Each review emphasizes the functional and mechanical aspects of a process, rather than the genetic aspects. We aim to make this resource accessible to a wide audience.
Topics focus on cellular structures and processes and are explored through two methods. Firstly their formation and function is presented, step-by-step, in the Steps in Formation, section. This is supplemented with a Functional Modules section which takes an in depth look at the cellular components that are common to the activity of several structures or processes.
Current Topics include:
Mechanobiology: When Cells Sense and Respond to their Environment
Cellular Structures in Mechanosensing and Cell Motility
Methods in the Study of Mechanobiology
Nuclear Mechanotransduction
Methods in the Study of Mechanobiology
Nuclear Mechanotransduction
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Suggestions and contributions from users are very important to the success of this resource. We invite all interested persons to contribute your information directly to MBInfo. If you are interested in becoming an MBInfo contributor, please click here.
For other suggestions, comments or questions please contact us at [email protected].
For other suggestions, comments or questions please contact us at [email protected].