Recent UpdatesApril 2013 Protein Domain Map tool introduced on each page Essential Info integrated into “Topics” with Updates March 2013 Glossary Term – Beta-Catenin Glossary Term – Actin – Updated description ‘Multiple Forms of Actin’ February 2013 Quizzes: What is Mechanobiology Quizzes: Actin Filaments and Microtubules December 2012 Functional Module: Activators and Integrin – Updated with Latest Findings October 2012Focal adhesion initiation – Updated with Latest Findings Functional Module: ADF/Cofilin – Updated with Latest Findings Edit function now active on each page September 2012 Dynamics of actin filament assembly– Updated with (Watch it on YouTube: Actin filament assembly) Focal adhesion initiation – Updated with ‘Latest Findings’ and figure Mechanisms of mechanosensing by FAs – Updated with a new model for ‘Stress driven mechanism’ of adhesion maturation Factors affecting FA formation, dynamics and function – Updated with stochastic models on dynamics of flowing actin at FAs Lamellipodia – Step 3: Focal adhesions as molecular clutch – Updated with stochastic models on how actin flow affects traction stress at adhesion sites Filopodia – Step 1: Initiation and Nucleation – Detail on “convergent elongation model” expanded Filopodia – Step 2: Extension – Latest findings update Lamellipodia – Step 2: Extension, Pause and Stasis – Expanded content August 2012 Nuclear Mechanotransduction– New topic! Invadopodia – Updated with interactive image! Cellular structures in mechanosensing and cell motility – Updated with interactive image! July 2012 Myosin Powerstroke figure – Updated to clearly depict each step in the powerstroke cycle. Nuclear Mechanics in Disease States – New section under ” What is the physiological relevance of mechanobiology?- Disease states” June 2012
Arp2/3-Mediated Nucleation: Functional Module – Updated with ‘Latest Findings’
Super Resolution Microscopy – New Unit under the topic “Methods in the Study of Mechanobiology”
Kinesin – New Glossary Term including images
Formin and Profilin in Actin Nucleation: Functional Module – Updated with ‘Latest Findings’
Focal adhesion dynamics – New section under “Focal adhesion formation: Overview” |