Recent Updates

June 2013
New help page describing MBInfo gadgets

April 2013
Protein Domain Map tool introduced on each page
Essential Info integrated into “Topics” with Updates
Images added to Glossary Term –  Beta-Catenin 

March 2013
Glossary Term – Beta-Catenin
Glossary Term – Actin – Updated description ‘Multiple Forms of Actin’

February 2013

December 2012
Functional Module: Activators and Integrin – Updated with Latest Findings
Focal adhesion initiation – Updated with Latest Findings


October 2012
Functional Module: ADF/Cofilin – Updated with Latest Findings
Edit function now active on each page

September 2012
Dynamics of actin filament assembly– Updated with (Watch it on YouTube: Actin filament assembly)
Focal adhesion initiation – Updated with ‘Latest Findings’ and figure
Mechanisms of mechanosensing by FAs – Updated with a new model for ‘Stress driven mechanism’ of adhesion maturation
Factors affecting FA formation, dynamics and function – Updated with stochastic models on dynamics of flowing actin at FAs
Lamellipodia – Step 3: Focal adhesions as molecular clutchUpdated with stochastic models on how actin flow affects traction stress at adhesion sites
Filopodia – Step 1: Initiation and Nucleation – Detail on “convergent elongation model” expanded
Filopodia – Step 2: Extension – Latest findings update

August 2012
Nuclear MechanotransductionNew topic!
Invadopodia – Updated with interactive image!
Cellular structures in mechanosensing and cell motilityUpdated with interactive image!

July 2012
Myosin Powerstroke figure – Updated to clearly depict each step in the powerstroke cycle.
Nuclear Mechanics in Disease StatesNew section under ” What is the physiological relevance of mechanobiology?- Disease states”

June 2012
Arp2/3-Mediated Nucleation: Functional Module – Updated with ‘Latest Findings’
Super Resolution MicroscopyNew Unit under the topic “Methods in the Study of Mechanobiology”
Kinesin New Glossary Term including images
Formin and Profilin in Actin Nucleation: Functional Module – Updated with ‘Latest Findings’
Focal adhesion dynamicsNew section under “Focal adhesion formation: Overview”
Focal adhesion maturation – Updated with ‘Latest Findings’ and interactive image!